Brain Regions for Semantic Memory

Figure 2. Brain regions showing differences between successful RM activity during encoding (ESA) and during retrieval (RSA). The bar graphs display differences in the effect size of activations for remembered versus forgotten items during encoding (i.e., subsequently remembered vs forgotten) and during retrieval (i.e., hits vs misses). Diff, Difference; Dorsolat, dorsolateral; ENC, encoding; Forg, forgotten; P, perceptual; Post. Parahipp./Hipp., posterior parahippocampal cortex/hippocampus; Rem, remembered; RET, retrieval; S, semantic; Ventrolat, ventrolateral. Enclosed box displays the MTL from a sagittal slice at x = -27.

Brain regions that showed ESA/RSA overlaps that differed between semantic (S) and perceptual (P) RM conditions (teal, semantic; purple, perceptual). The left ventrolateral (L Ventrolat) PFC region (BA 45; x, y, z: -46, 26, 2) was slightly more posterior/dorsal than the left ventrolateral PFC region that showed greater ESA than RSA for both semantic and perceptual RM (red area, BA 47; x, y, z: -49, 33, -8). B Parietal, Bilateral parietal cortex; Diff, difference; ENC, encoding; Forg, forgotten; L Occiptemp, left occipitotemporal cortex; R Post Parahipp G, right posterior parahippocampal cortex/hippocampus; Rem, remembered; RET, retrieval. (Prince et al, 2005)

Reference:

Prince, S.E., Daselaar, S.M., & Cabeza, R. (2005). Neural correlates of relational memory: successful encoding and retrieval of semantic and perceptual associations. The Journal of Neuroscience. 25(5), 1203-1210.